Algiamed Research
At Algiamed Technologies, we are in awe of the body’s natural ability to regulate its internal control systems (nervous -, endocrine -, circulatory -, respiratory -, systems, etc.) maintaining a seemingly miraculous state of balance and harmony at its optimum state of vibrant health.
We’re so intrigued by the extraordinary intelligence (centralized and de-centralized) and complexity of the information systems involved in maintaining the most rudimentary functions within our living organism that we’ve challenged ourselves to characterize the unexplored aspects of this complex system to better understand it’s decision making processes and centers as well as how this information is mediated.
We are equally intrigued by the origin of pathologies, how this near-perfect state of harmony can become disrupted by some known or unknown pathogenesis, causing unwelcome adaptations within this communication network which in turn results in a state of dis-ease.
Our research is focused on decoding the complexities of the body’s information systems and control systems and how the introduction of non-harmful stimuli can potentially reverse maladapted or pathological control systems and return it back to its natural state of function.
1. Can weak magnetic fields change gene-expression?
Type of Research: Literature review
Team: F. Marsili , C.F. Birkill
Status: Completed
Quantum Biology and Healthcare: the Synergistic Bioeffect of Weak Electromagnetic Fields (EMFs) on Human Bodies
Abstract
Human bodies are constantly exposed to environmental electromagnetic sources. Both electric and magnetic fields are known to have an active role in altering biological activities. In the present report, the focus will be exclusively on investigating the role of physiological exposure to magnetism. While strong magnetic fields (MFs) are known to induce potentially harmful thermal effects on living systems, there is no existing evidence suggesting possible negative side effects on biological systems from exposure to low-intensity magnetic fields. In recent years, the fast-growing field of quantum biology has focused on characterizing the complex interactions initiated by weak magnetic fields on human bodies through the laws of quantum physics. Even though there is still little understanding of the exact mechanisms, there is sufficient evidence demonstrating short- and long-term physiological changes elicited and, possibly controlled, by magnetic sources. This paper presents a summary of the mechanisms that are potentially, and possibly mutually, involved in eliciting biological reactions to magnetic exposure, supported by experimental evidence. The current understanding of human electromagnetic exposure suggests a potential future role of electromagnetic therapies as non-invasive, effective, and well-tolerated treatments for chronic and acute illnesses.
2. Can weak electric fields change gene-expression?
Type of Research: Literature review and experimental
Team: P. van Blerk, P. Potgieter, C.F. Birkill
Status: In Process
3. Characterizing the propagation pathway of a transcutaneously applied RF waveform to a targeted neural mitochondria
Type of Research: Mathematical model
Team: P. Potgier, C.F. Birkill
Status: In Process
4. Diabetic Neuropathy pathogenesis and progression from a control system perspective
Type of Research: Literature review
Team: F. Marsili, P. Potgieter, C.F. Birkill.
Status: Published
Published Article: Adaptive Autonomic and Neuroplastic Control in Diabetic Neuropathy: A Narrative Review
Background
Type 2 diabetes mellitus (T2DM) is a worldwide socioeconomic burden, and is accompanied by a variety of metabolic disorders, as well as nerve dysfunction referred to as diabetic neuropathy (DN). Despite a tremendous body of research, the pathogenesis of DN remains largely elusive. Currently, two schools of thought exist regarding the pathogenesis of diabetic neuropathy: a) mitochondrial-induced toxicity, and b) microvascular damage. Both mechanisms signify DN as an intractable disease and, as a consequence, therapeutic approaches treat symptoms with limited efficacy and risk of side effects.
Objective
Here, we propose that the human body exclusively employs mechanisms of adaptation to protect itself during an adverse event. For this purpose, two control systems are defined, namely the autonomic and the neural control systems. The autonomic control system responds via inflammatory and immune responses, while the neural control system regulates neural signaling, via plastic adaptation. Both systems are proposed to regulate a network of temporal and causative connections which unravel the complex nature of diabetic complications.
Results
A significant result of this approach infers that both systems make DN reversible, thus opening the door to novel therapeutic applications.
5. Temporal characteristics of microstructural changes due to gene expression activation and adaptation in Diabetic Neuropathy
Type of Research: Literature review
Team: F. Marisili, P. Potgieter, C.F Birkill
Status: In Process